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frequently-asked-questions-faq [2015/10/23 11:32]
127.0.0.1 external edit
frequently-asked-questions-faq [2018/07/31 18:17] (current)
thorsten
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 \\ Calculators to estimate the sample size to demonstrate freedom from disease should not be applied as calculations may lead to inadequate samples sizes given that positives are known to be present. Similarly, calculators to estimate sensitivity are not truly applicable as they operate under the assumption that no positives are found. Calculators to estimate the probability of detecting disease (sensitivity) however can still be applied to calculate the the theoretical sensitivity of the surveillance component / system. This theoretical sensitivity can be used to provide an indication of the effort made and thus to allow comparing different surveillance systems in low-prevelance situations. In additiona, true prevalence and 95% confidence Limits need to be calculated to allow monitoring changes in prevalence over time.\\ \\ \\  \\ Calculators to estimate the sample size to demonstrate freedom from disease should not be applied as calculations may lead to inadequate samples sizes given that positives are known to be present. Similarly, calculators to estimate sensitivity are not truly applicable as they operate under the assumption that no positives are found. Calculators to estimate the probability of detecting disease (sensitivity) however can still be applied to calculate the the theoretical sensitivity of the surveillance component / system. This theoretical sensitivity can be used to provide an indication of the effort made and thus to allow comparing different surveillance systems in low-prevelance situations. In additiona, true prevalence and 95% confidence Limits need to be calculated to allow monitoring changes in prevalence over time.\\ \\ \\ 
  
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